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Pasteur's Quadrant: Basic Science and Technological Innovation Donald E. Stokes
Publisher: Brookings Institution Press

Stokes DE: Pasteur's quadrant: Basic science and technological innovation. One way of making this distinction is in the terms introduced in the infrequently read but oft cited 1997 book by Stokes, called Pasteur's Quadrant – Basic Science and Technological Innovation. In recent years the concept of "translational medicine" has been advanced in an attempt to catalyze the medical applications of basic biomedical research. Collectively, these core technologies could permit the development of an innovative pharmaceutical platform composed of nanoparticles with tethered small interfering RNA (siRNA) oligonucelotides whose sequence and objective can be reprogrammed “on-the-fly” to inhibit multiple targets within multiple classes of And the first element in DARPA's success is the power that lies at the intersection of basic science and application, in the so-called Pasteur's Quadrant. Speculation on science, technology, and society. Eschewing Vannevar Bush's model of separation between 'pure, untainted' research and that influenced by considerations of use, see Donald Stokes' excellent book "Pasteur's Quadrant: Basic Science and Technological Innovation. My suggestion "Pasteur's Quadrant: Basic Science and Technological Innovation" by Donald Stokes. As conventional wisdom has it, basic research is a core input for economic innovation, and economic innovation is good for everybody. ʼn�两天看到一篇关于Pasteur's Quadrant这本书的评论，感觉有些意思，有时间再慢慢翻译出来，这里先贴出原文。 Pasteur's Quadrant: Basic Science and Technological Innovation/Chaos of Disciplines. The issues are informed by my experiences in the TSSG, where we conduct most of our research in Pasteur's Quadrant and in Edison's Quadrant. Stokes DE: Pasteur's quadrant: basic science and technological innovation. Issues of terminology around the idea of "Basic Research" in Science, Engineering and Technology. Unless on subscribes to some species of idealism or essentialism, strictly speaking the term basic or fundamental research has no meaning outside its use as a statistical household word: in other words it is historically and socially contingent . His favorite example of “use-inspired basic research” is Louis Pasteur's repeated success in working on genuine problems such as the spoilage of milk and failures of wine fermentation, to produce basic science breakthroughs about bacterial processes and vaccines. "New knowledge can be obtained only through basic scientific research" conducted in universities and research labs, which is then applied to develop new products by the private sector and new and improved weapons by the defense . But really, when you look In essence, Bell Labs took the best in the world and aimed them towards “use-inspired basic research”, what science policy scholar, academic administrator, and NSF advisor Donald Stokes identified as Pasteur's Quadrant. Yet a number of senior public servants, myself included, believe passionately in the pivotal role of research and technology in building a modern economy and society, and worked with successive governments over the last 15 years .. Donald Stokes (Pascal's Quadrant: Basic Science and Technological Innovation, 1997) stresses work that is motivated by both considerations for use and fundamental understanding. Traditional government policies suggest that upstream investment in scientific research is necessary and sufficient to generate technological innovations. Having said this, there is a lot of research going on in MS.